Bacteriophage P2

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The C repressor of the P2 bacteriophage

The C-repressor of bacteriophage P2 (P2 C) is a DNAbinding protein that controls the lifecycle of the P2 bacteriophage by directing it toward the lysogenic mode. P2 C is a 99 amino acids protein, which forms stable homodimers but not higher oligomers in the absence of DNA (Ahlgren-Berg et al. 2007). As opposed to the more common situation where dimeric proteins bind palindromic DNA-sequences, P...

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Complete Genome Sequence of the Pseudomonas fluorescens Bacteriophage UFV-P2

Milk proteolysis caused by Pseudomonas fluorescens is a serious problem in the dairy industries as a result of its ability to grow under refrigeration. The use of phages to control contaminants in food has been considered an alternative to traditional methods; therefore, a thorough understanding of such organisms is vital for their use. In this study, we show the complete genome sequence and an...

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An Escherichia coli Gene Required for Bacteriophage P2-K Interference

The gene old of bacteriophage P2 is known to (i) cause interference with phage A growth; (ii) kill recBmutants of Escherichia coli after P2 infection; and (iii) determine increased sensitivity of P2 lysogenic cells to X-ray irradiation. In all of these phenomena, inhibition of protein synthesis occurs. We have isolated bacterial mutants, named pin (P2 interference), able to suppress all of the ...

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Regulation of bacteriophage P2 late-gene expression: the ogr gene.

The ogr gene product of bacteriophage P2 is a positive regulatory factor required for P2 late-gene transcription. We have determined the nucleotide sequence of the ogr gene, which encodes a basic polypeptide of 72 amino acids. P2 growth is blocked by a host mutation, rpoA109, in the alpha subunit of DNA-dependent RNA polymerase. The ogr52 mutation, which allows P2 to grow in an rpoA109 strain, ...

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ژورنال

عنوان ژورنال: Bacteriophage

سال: 2016

ISSN: 2159-7081

DOI: 10.1080/21597081.2016.1145782